Search Ontology:
ChEBI
dCeMM4
- Term ID
- CHEBI:232058
- Synonyms
-
- 3-[(5-methylfuran-2-yl)carbonyl]-N-(5-methyl-1,3-thiazol-2-yl)-1,3-thiazolidine-4-carboxamide
- Definition
- A furan that is substituted by {4-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]-1,3-thiazolidin-3-yl}carbonyl and methyl groups at positions 2 and 5, respectively. It is a glue degrader that induces the ubiquitination and degradation of cyclin K by prompting an interaction between CDK12:cyclin K with a CRL4B ligase complex.
- References
-
- CAS:1281683-44-0
- PMID:32747809
- PMID:34131295
- PMID:35682885
- PMID:36176907
- PMID:37679459
- PMID:38582446
- Ontology
- ChEBI ( EBI )
- is a type of
-
Phenotype
Phenotype resulting from dCeMM4
Phenotype where environments contain dCeMM4
Phenotype modified by environments containing dCeMM4
Human Disease Model