Search Ontology:
ChEBI

dCeMM4

Term ID
CHEBI:232058
Synonyms
  • 3-[(5-methylfuran-2-yl)carbonyl]-N-(5-methyl-1,3-thiazol-2-yl)-1,3-thiazolidine-4-carboxamide
Definition
A furan that is substituted by {4-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]-1,3-thiazolidin-3-yl}carbonyl and methyl groups at positions 2 and 5, respectively. It is a glue degrader that induces the ubiquitination and degradation of cyclin K by prompting an interaction between CDK12:cyclin K with a CRL4B ligase complex.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
Phenotype
Phenotype resulting from dCeMM4
Phenotype where environments contain dCeMM4
Phenotype modified by environments containing dCeMM4
Human Disease Model