tirbanibulin

Term ID

CHEBI:231702

Synonyms

5-[4-[2-(4-morpholinyl)ethoxy]phenyl]-N-(phenylmethyl)-2-pyridineacetamide
Klisyri
KX 01
KX-01
KX-2-391
KX-2391
KX01
KX2-391
N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetamide
N-benzyl-2-(5-{4-[2-(morpholin-4-yl)ethoxy]phenyl}pyridin-2-yl)acetamide
N-benzyl-5-(4-(2-morpholinoethoxy)phenyl)picolinamide
tirbanibulin
tirbanibulin free base
tirbanibulina
tirbanibuline
tirbanibulinum

(all 16)

Definition

A member of the class of pyridines that is pyridine substituted by 2-(benzylamino)-2-oxoethyl and 4-[2-(morpholin-4-yl)ethoxy]phenyl groups at positions 2 and 5, respectively. It is a dual inhibitor of Src kinase and tubulin and approved by the FDA for the topical treatment of actinic keratosis on the face or scalp.

References

(all 36)

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether morpholines pyridines secondary carboxamide

aromatic ether morpholines pyridines secondary carboxamide Show first 5 Terms
has_role: antineoplastic agent apoptosis inducer EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor microtubule-destabilising agent

antineoplastic agent apoptosis inducer EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor microtubule-destabilising agent Show first 5 Terms

Phenotype

Phenotype resulting from tirbanibulin

Phenotype where environments contain tirbanibulin

Phenotype modified by environments containing tirbanibulin

Phenotype affecting tirbanibulin

Human Disease Model