pluripotin

Term ID

CHEBI:231689

Synonyms

• N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
• N-(3-{7-[(1,3-dimethyl-1H-pyrazol-5-yl)amino]-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl}-4-methylphenyl)-3-(trifluoromethyl)benzamide
• SC 1
• SC1

Definition

A member of the class of pyrimidopyrimidines that is 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one substituted by methyl, 2-methyl-5-[3-(trifluoromethyl)benzamido]phenyl, and (1,3-dimethyl-1H-pyrazol-5-yl)amino group at positions 1, 3, and 7, respectively. It is a dual inhibitor of ERK1 and RasGAP.

References

• cas:839707-37-8
• pubmed:17088537
• pubmed:19056907
• pubmed:19924098
• pubmed:22564971
• pubmed:23437320
• pubmed:30153003
• pubmed:32203790

Ontology

ChEBI  ( EBI )