Search Ontology:
ChEBI

SF2523

Term ID
CHEBI:231676
Synonyms
  • 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(4-morpholinyl)-7H-thieno[3,2-b]pyran-7-one
  • 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(morpholin-4-yl)-7H-thieno[3,2-b]pyran-7-one
  • 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5-morpholino-7H-thieno[3,2-b]pyran-7-one
  • SF 2523
  • SF-2523
Definition
A member of the class of thienopyrans that is 7H-thieno[3,2-b]pyran-7-one substituted by 2,3-dihydro-1,4-benzodioxin-6-yl and morpholin-4-yl groups at positions 3 and 5, respectively. It is a dual inhibitor of PI3K and BRD4 that exhibits antineoplastic activity.
References
  • cas:1174428-47-7
  • pdb-ccd:82V
  • pubmed:23410005
  • pubmed:27559828
  • pubmed:28137841
  • pubmed:29133261
  • pubmed:29139214
  • pubmed:29228703
  • pubmed:29475942
  • pubmed:30824188
  • pubmed:31018997
  • pubmed:33480647
  • pubmed:34634662
  • pubmed:34926269
  • pubmed:35633739
  • pubmed:35942234
  • pubmed:36599397
  • pubmed:37042063
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from SF2523
Phenotype where environments contain SF2523
Phenotype modified by environments containing SF2523
Phenotype affecting SF2523
Human Disease Model