Search Ontology:
ChEBI
tasisulam
- Term ID
- CHEBI:231621
- Synonyms
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- LY 573636
- LY-573636
- LY573636
- N-(2,4-dichlorobenzoyl)-5-bromothiophene-2-sulfonamide
- N-(5-bromothiophen-2-yl)sulfonyl-2,4-dichlorobenzamide
- N-[(5-bromothiophen-2-yl)sulfonyl]-2,4-dichlorobenzamide
- tasisulam
- tasisulamum
- Definition
- A thiophene substituted by a 2,4-dichlorobenzamide-N-sulfonyl and bromo groups at positions 2 and 4, respectively. It induces tumour cell apoptosis via ROS induction and mitochondrial membrane potential loss and currently in clinical development for the treatment of cancer.
- References
-
- CAS:519055-62-0
- DrugBank:DB11941
- PDBeChem:P7M
- PMID:18949427
- PMID:21431416
- PMID:21456002
- PMID:21903607
- PMID:22539091
- PMID:22588156
- PMID:23228983
- PMID:23370664
- PMID:24676877
- PMID:25260842
- PMID:28013301
- PMID:29119333
- PMID:30793132
- PMID:31686031
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from tasisulam
Phenotype where environments contain tasisulam
Phenotype modified by environments containing tasisulam
Human Disease Model