XMU-MP-1

Term ID

CHEBI:231615

Synonyms

4-((5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino)benzenesulfonamide
4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide
XMU MP 1
XMU-MP1

Definition

An organic heterotricyclic compound that is 5,10-dihydro-6H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-6-one substituted by (4-sulfamoylphenyl)amino, methyl and methyl groups at positions 2, 5 and 10, respectively. It is an inhibitor of the Hippo pathway kinases MST1 and MST2 (IC50 = 71.1 and 38.1 nM, respectively).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: organic heterotricyclic compound secondary amino compound sulfonamide tertiary amino compound

organic heterotricyclic compound secondary amino compound sulfonamide tertiary amino compound Show first 5 Terms
has_role: bone density conservation agent cardioprotective agent EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor hepatoprotective agent

bone density conservation agent cardioprotective agent EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor hepatoprotective agent Show first 5 Terms

Phenotype

Phenotype resulting from XMU-MP-1

Phenotype where environments contain XMU-MP-1

Phenotype modified by environments containing XMU-MP-1

Human Disease Model