AM6545

Term ID

CHEBI:231613

Synonyms

5-[4-(4-cyanobut-1-yn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxidothiomorpholin-4-yl)-4-methyl-1H-pyrazole-3-carboxamide
5-[4-(4-cyanobut-1-yn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxo-1lambda(6),4-thiazinan-4-yl)-4-methyl-1H-pyrazole-3-carboxamide
5-[4-(4-cyanobut-1-yn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxo-1lambda(6)-thiomorpholin-4-yl)-4-methyl-1H-pyrazole-3-carboxamide
AM 6545
AM-6545

Definition

A member of the class of pyrazoles that is 1H-pyrazole substituted by 2,4-dichlorophenyl, N-(1,1-dioxidothiomorpholin-4-yl)aminoacyl, methyl, and 4-(4-cyanobut-1-yn-1-yl)phenyl groups at positions 1, 3, 4 and 5, respectively. It is a cannabinoid receptor 1 antagonist and a potential appetite suppressant.

References

cas:1245626-05-4
hmdb:HMDB0248271
pubmed:20664173
pubmed:20713079
pubmed:20880401
pubmed:23902803
pubmed:25772338
pubmed:26426981
pubmed:28144708
pubmed:28387811
pubmed:29615900
pubmed:30184259
pubmed:31281260
pubmed:32927872
pubmed:32987186
pubmed:33121353
pubmed:33138155
pubmed:33216305
pubmed:33562080
pubmed:33998896
pubmed:35787179
pubmed:36088492
pubmed:36682621
pubmed:37212036
pubmed:38059442
pubmed:38398671
pubmed:38594069
wikipedia.en:AM-6545

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from AM6545

Phenotype where environments contain AM6545

Phenotype modified by environments containing AM6545

Phenotype affecting AM6545

Human Disease Model