Search Ontology:
ChEBI

ITK7

Term ID
CHEBI:231599
Synonyms
  • 8-methyl-7-(prop-1-yn-1-yl)-2-((pyrimidin-2-ylthio)methyl)quinazolin-4(3H)-one
  • 8-methyl-7-(prop-1-yn-1-yl)-2-[(pyrimidin-2-ylsulfanyl)methyl]quinazolin-4(3H)-one
  • 8-methyl-7-prop-1-ynyl-2-(pyrimidin-2-ylsulfanylmethyl)-3H-quinazolin-4-one
  • ITK 7
  • ITK-7
  • PARP11 inhibitor ITK7
Definition
A member of the class of quinazolines that is quinazolin-4(3H)-one substituted by (pyrimidin-2-ylsulfanyl)methyl, prop-1-yn-1-yl, and methyl groups at positions 2, 7, and 8, respectively. It is a potent PARP11 inhibitor (IC50 = 14 nM).
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from ITK7
Phenotype where environments contain ITK7
Phenotype modified by environments containing ITK7
Human Disease Model
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