Search Ontology:
ChEBI
sulfopin
- Term ID
- CHEBI:231413
- Synonyms
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- 2-chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-neopentylacetamide
- 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)acetamide
- 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxo-1lambda(6)-thiolan-3-yl)acetamide
- PIN1-3
- Definition
- A sulfone that is thiolane substituted by two oxo groups at position 1 and by a (chloroacetyl)(2,2-dimethylpropyl)amino group at position 3. It is a covalent inhibitor of Pin1 (Ki = 17 nM) that inhibits Myc-driven tumors in vivo.
- References
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- CAS:2451481-08-4
- PMID:33972797
- PMID:38167292
- PMID:38550694
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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Phenotype
Phenotype resulting from sulfopin
Phenotype where environments contain sulfopin
Phenotype modified by environments containing sulfopin
Human Disease / Model Data
Citations