telatinib

Term ID

CHEBI:231351

Synonyms

4-(((4-((4-chlorophenyl)amino)furo[2,3-d]pyridazin-7-yl)oxy)methyl)-N-methylpicolinamide
4-({[4-(4-chloroanilino)furo[2,3-d]pyridazin-7-yl]oxy}methyl)-N-methylpyridine-2-carboxamide
4-[[[4-[(4-chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl]oxy]methyl]-N-methyl-2-pyridinecarboxamide
BAY 57-9352
BAY-57-9352
BAY-579352
telatinib
telatinibum

Definition

A member of the class of furopyridazines that is furo[2,3-d]pyridazine substituted by (4-chlorophenyl)amino and [2-(methylcarbamoyl)pyridin-4-yl]methoxy groups at positions 4 and 7, respectively. It is a potent inhibitor of VEGFR2/3, c-Kit and PDGFRalpha.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: anilines aromatic ether furopyridazine monochlorobenzenes pyridinecarboxamide

anilines aromatic ether furopyridazine monochlorobenzenes pyridinecarboxamide Show first 5 Terms
has_role: angiogenesis inhibitor antineoplastic agent apoptosis inducer EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor vascular endothelial growth factor receptor antagonist

angiogenesis inhibitor antineoplastic agent apoptosis inducer EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor vascular endothelial growth factor receptor antagonist Show first 5 Terms

Phenotype

Phenotype resulting from telatinib

Phenotype where environments contain telatinib

Phenotype modified by environments containing telatinib

Human Disease Model