Ac-Tyr-Val-Ala-Asp-chloromethylketone

Term ID

CHEBI:230455

Synonyms

Ac-L-Tyr-L-Val-L-Ala-L-Asp-chloromethylketone
Ac-YVAD-cmk
N-acetyl-L-tyrosyl-L-valyl-N-[(2S)-1-carboxy-4-chloro-3-oxobutan-2-yl]-L-alaninamide
N-acetyl-tyrosinyl-valinyl-alanyl-aspartyl chloromethyl ketone
N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone
N-acetyltyrosinylvalinylalanylaspartylchloromethyl ketone

Definition

A tetrapeptide composed of L-tyrosine, L-valine, L-alanine, and L-aspartic acid joined in sequence by peptide linkages and in which the amino terminus in substituted by an acetyl group and the carboxy terminus is substituted by a chloromethyl group.

References

cas:178603-78-6
hmdb:HMDB0249697
pubmed:11015286
pubmed:20596246
pubmed:27053298
pubmed:28245402
pubmed:28855128
pubmed:29382416
pubmed:30410928
pubmed:30473634
pubmed:30496753
pubmed:30571969
pubmed:31352322
pubmed:33509083
pubmed:33647825
pubmed:33914736
pubmed:34222479
pubmed:34624334
pubmed:36629424
pubmed:36696410
pubmed:36870601
pubmed:37144237
pubmed:37179200
pubmed:37380608
pubmed:37620837
pubmed:37859698
pubmed:38383487

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from Ac-Tyr-Val-Ala-Asp-chloromethylketone

Phenotype where environments contain Ac-Tyr-Val-Ala-Asp-chloromethylketone

Phenotype modified by environments containing Ac-Tyr-Val-Ala-Asp-chloromethylketone

Phenotype affecting Ac-Tyr-Val-Ala-Asp-chloromethylketone

Human Disease Model