pifithrin-alpha hydrobromide

Term ID

CHEBI:229924

Synonyms

2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3(2H)-yl)-1-(4-methylphenyl)ethanone hydrobromide
2-(2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone hydrobromide
PFT-alpha
PFTalpha
pifithrin-alpha

Definition

A hydrobromide salt prepared from 2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone and one equivalent of hydrogen bromide. It is a chemical that inhibits p53-mediated gene activation and apoptosis.

References

cas:63208-82-2
chemspider:19952120
pubmed:10481009
pubmed:12085641
pubmed:12884365
pubmed:14766674
pubmed:15185296
pubmed:15843497
pubmed:16258175
pubmed:16687611
pubmed:17065086
pubmed:17673346
pubmed:17877294
pubmed:18317410
pubmed:18364113
pubmed:18418056
pubmed:19229248
pubmed:19267667
pubmed:19409072
pubmed:19913499
pubmed:20092569
pubmed:20348016
pubmed:24472721
pubmed:24868967
pubmed:25448278
pubmed:25470941
pubmed:29278895
pubmed:31069753
pubmed:33852931
pubmed:37298128

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from pifithrin-alpha hydrobromide

Phenotype where environments contain pifithrin-alpha hydrobromide

Phenotype modified by environments containing pifithrin-alpha hydrobromide

Phenotype affecting pifithrin-alpha hydrobromide

Human Disease Model