WZB-117

Term ID

CHEBI:229781

Synonyms

3-fluoro-1,2-phenylene bis(3-hydroxybenzoate)
3-fluorobenzene-1,2-diyl bis(3-hydroxybenzoate)
3-hydroxy-benzoic acid 1,1'-(3-fluoro-1,2-phenylene) ester
WZB 117
WZB117

Definition

A diester resulting from the formal condensation of the two hydroxy groups of 3-fluorocatechol with the carboxy groups of 3-hydroxybenzoic acid. It is an inhibitor of glucose transporter 1 (GLUT1) that suppresses tumour growth in mouse xenograft models.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: benzoate ester diester monofluorobenzenes phenols

benzoate ester diester monofluorobenzenes phenols Show first 5 Terms
has_functional_parent: 3-fluorocatechol 3-hydroxybenzoic acid

3-fluorocatechol 3-hydroxybenzoic acid Show first 5 Terms
has_role: antineoplastic agent glucose transporter 1 inhibitor radiosensitizing agent

antineoplastic agent glucose transporter 1 inhibitor radiosensitizing agent Show first 5 Terms

Phenotype

Phenotype resulting from WZB-117

Phenotype where environments contain WZB-117

Phenotype modified by environments containing WZB-117

Human Disease / Model Data

Citations