selinexor

Term ID

CHEBI:229764

Synonyms

(2Z)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1- yl}-N'-(pyrazin-2-yl)prop-2-enehydrazide
(2Z)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-N'-(pyrazin-2-yl)prop-2-enehydrazide
KPT 330
KPT-330
selinexor
selinexorum
Xpovio

Definition

A member of the class of triazoles that is 1H-1,2,4-triazole substituted by (1Z)-3-oxo-3-[2-(pyrazin-2-yl)hydrazinyl]prop-1-en-1-yl and 3,5-bis(trifluoromethyl)phenyl groups at positions 1 and 3, respectively. It is a prescription medicine approved for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma.

References

drugbank:DB11942
hmdb:HMDB0258217
kegg.drug:D11222
pubmed:23373539
pubmed:27893412
pubmed:28314790
pubmed:28810913
pubmed:28852098
pubmed:29707241
pubmed:30064906
pubmed:30115935
pubmed:30996012
pubmed:32598257
pubmed:33403670
pubmed:33507295
pubmed:33601919
pubmed:34488662
pubmed:34669417
pubmed:34741230
pubmed:35355406
pubmed:35477814
pubmed:35667526
pubmed:35941226
pubmed:36180918
pubmed:36200270
pubmed:36622814
pubmed:36731340
pubmed:36827679
pubmed:36847599
pubmed:37016732
pubmed:37046649
pubmed:37047788
pubmed:37079389
pubmed:37094850
pubmed:37126200
pubmed:37175668
pubmed:37184196
pubmed:37191210
pubmed:37346402
pubmed:37595020
pubmed:37715291
pubmed:37760508
pubmed:37945593
pubmed:38105606
pubmed:38186637
pubmed:38454813
wikipedia.en:Selinexor

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from selinexor

Phenotype where environments contain selinexor

Phenotype modified by environments containing selinexor

Phenotype affecting selinexor

Human Disease Model