ritlecitinib

Term ID

CHEBI:229233

Synonyms

1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
PF 06651600
PF-06651600
PF06651600
ritlecitinib
ritlecitinibum

Definition

A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted at position 4 by a [(3R,6S)-6-methyl-1-(prop-2-enoyl)piperidin-3-yl]amino group. It is a dual inhibitor of Janus kinase 3 and the TEC family of tyrosine kinases.

References

cas:1792180-81-4
drugbank:DB14924
pubmed:31082193
pubmed:32419304
pubmed:33757798
pubmed:34826225
pubmed:35000236
pubmed:35210753
pubmed:35732501
pubmed:36623678
pubmed:36807251
pubmed:36808638
pubmed:36872080
pubmed:36977960
pubmed:37062298
pubmed:37403610
pubmed:37455588
pubmed:37521227
pubmed:37550228
pubmed:37556041
pubmed:37561322
pubmed:37691236
pubmed:37707764
pubmed:37777018
pubmed:37812490
pubmed:37917289
pubmed:38051245
pubmed:38051803
pubmed:38141256
wikipedia.en:Ritlecitinib

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from ritlecitinib

Phenotype where environments contain ritlecitinib

Phenotype modified by environments containing ritlecitinib

Phenotype affecting ritlecitinib

Human Disease Model