Search Ontology:
ChEBI
sotagliflozin
- Term ID
- CHEBI:229226
- Synonyms
-
- (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)- 6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol
- (2S,3R,4R,5S,6R)-2-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-(methylsulfanyl)tetrahydro-2H-pyran-3,4,5-triol
- (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(methylsulfanyl)oxane-3,4,5-triol
- Inpefa
- LP-802034
- LX 4211
- LX-4211
- LX4211
- methyl (5S)-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-1-thio-beta-L-xylopyranoside
- sotagliflozin
- sotagliflozina
- sotagliflozine
- sotagliflozinum
- Zynquista
- Definition
- An S-glycosyl compound that is 1-thio-beta-L-xylopyranose in which the anomeric hydroxy group is replaced by a 4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl group and the thiol is replaced by a methylsulfanediyl group. It is an inhibitor of SGLT1 and SGLT2 that is approved to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes mellitus, chronic kidney disease, and other cardiovascular risk.
- References
-
- CAS:1018899-04-1
- DrugBank:DB12713
- HMDB:HMDB0258396
- KEGG:D10669
- PDBeChem:LFL
- PMID:22739142
- PMID:33108240
- PMID:33235374
- PMID:33704413
- PMID:33764842
- PMID:33852786
- PMID:33852787
- PMID:33852788
- PMID:34181127
- PMID:34338408
- PMID:34545668
- PMID:36330901
- PMID:36370667
- PMID:36718512
- PMID:36782093
- PMID:36872068
- PMID:37045523
- PMID:37172207
- PMID:37258583
- PMID:37318685
- PMID:37402421
- PMID:37427762
- PMID:37460142
- PMID:37523069
- PMID:37558385
- PMID:37586658
- PMID:37868384
- PMID:37914514
- PMID:37914515
- PMID:38014844
- PMID:38031239
- PMID:38044937
- PMID:38058609
- PMID:38141092
- PMID:38225341
- PMID:38527859
- PMID:38578622
- Wikipedia:Sotagliflozin
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from sotagliflozin
Phenotype where environments contain sotagliflozin
Phenotype modified by environments containing sotagliflozin
Human Disease / Model Data