Search Ontology:
ChEBI
daprodustat
- Term ID
- CHEBI:229223
- Synonyms
-
- daprodustat
- daprodustatum
- GSK 1278863
- GSK-1278863
- GSK1278863
- Jesduvroq
- N-[(1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidin-5-yl)carbonyl]glycine
- {[(1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidin-5-yl)carbonyl]amino}acetic acid
- Definition
- A member of the class of barbiturates that is barbituric acid substituted by cyclohexyl groups at positions 1 and 3, and by a (carboxymethyl)aminocarbonyl group at position 5. It is an inhibitor of hypoxia-inducible factor prolyl hydroxylase developed by GlaxoSmithKline for the treatment of anaemia in patients with chronic kidney disease.
- References
-
- CAS:960539-70-2
- DrugBank:DB11682
- HMDB:HMDB0250863
- KEGG:D10874
- PMID:25343825
- PMID:31640478
- PMID:32880805
- PMID:34739196
- PMID:34824467
- PMID:35191925
- PMID:35281917
- PMID:35355447
- PMID:35380500
- PMID:35534679
- PMID:35628849
- PMID:35639861
- PMID:35643373
- PMID:35983622
- PMID:36181513
- PMID:36195739
- PMID:36372403
- PMID:36565721
- PMID:36577110
- PMID:36577111
- PMID:36577112
- PMID:36739866
- PMID:36780413
- PMID:36868377
- PMID:37026612
- PMID:37116458
- PMID:37125459
- PMID:37156672
- PMID:37516063
- PMID:37637409
- PMID:37885335
- PMID:37926547
- PMID:38261926
- PMID:38412265
- Wikipedia:Daprodustat
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from daprodustat
Phenotype where environments contain daprodustat
Phenotype modified by environments containing daprodustat
Human Disease Model