Search Ontology:
ChEBI

fruquintinib

Term ID
CHEBI:229221
Synonyms
  • 6-[(6,7-dimethoxyquinazolin-4-yl)oxy]-N,2-dimethyl-1-benzofuran-3-carboxamide
  • fruquintinib
  • fruquintinibum
  • Fruzaqla
  • HMPL-013
Definition
A member of the class of quinazolines that is quinazoline substituted by [2-methyl-3-(methylcarbamoyl)-1-benzofuran-6-yl]oxy, methoxy, and methoxy groups at positions 4, 6, and 7, respectively. It is a highly potent and selective inhibitor of VEGFR 1, 2 and 3 (IC50 = 33, 0.35, and 35 nM) used for the treatment of metastatic colorectal cancer.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from fruquintinib
Phenotype where environments contain fruquintinib
Phenotype modified by environments containing fruquintinib
Human Disease Model
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