Search Ontology:
ChEBI
elacestrant
- Term ID
- CHEBI:229213
- Synonyms
-
- (6R)-6-[2-(ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
- (R)-6-(2-(ethyl(4-(2-(ethylamino)ethyl)benzyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol
- elacestrant
- elacestrantum
- ER-306323
- Orserdu
- RAD 1901
- RAD-1901
- RAD1901
- Definition
- A member of the class of tetralins that is 1,2,3,4-tetrahydronaphthalene which is substituted by hydroxy group at position 2 and by a 2-(ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl group at position 6R. It is a is an estrogen receptor degrader indicated for the treatment of postmenopausal women or adult men, with ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer with disease progression following at least one line of endocrine therapy.
- References
-
- CAS:722533-56-4
- DrugBank:DB06374
- KEGG:D11671
- PDBeChem:I0V
- PMCID:PMC10554897
- PMID:28473534
- PMID:31426673
- PMID:31852484
- PMID:33513026
- PMID:33589422
- PMID:34798371
- PMID:35348779
- PMID:35621343
- PMID:35737918
- PMID:36446866
- PMID:36813113
- PMID:36877283
- PMID:36960661
- PMID:36993871
- PMID:37060385
- PMID:37143269
- PMID:37191763
- PMID:37314500
- PMID:37318638
- PMID:37364222
- PMID:37485921
- PMID:37580832
- PMID:37594177
- PMID:37888769
- PMID:38006464
- PMID:38039056
- PMID:38169749
- Wikipedia:Elacestrant
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Show All 6 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from elacestrant
Phenotype where environments contain elacestrant
Phenotype modified by environments containing elacestrant
Human Disease / Model Data
Citations