Search Ontology:
ChEBI
KRIBB11
- Term ID
- CHEBI:228800
- Synonyms
-
- N(2)-(1H-indazol-5-yl)-N(6)-methyl-3-nitropyridine-2,6-diamine
- N(2)-1H-indazol-5-yl-N(6)-methyl-3-nitro-2,6-pyridinediamine
- Definition
- A member of the class of indazoles that is 1H-indazole substituted by a [6-(methylamino)-3-nitropyridin-2-yl]amino group at position 5. It is an inhibitor of heat shock factor 1 (IC50 = 1.2muM) and suppresses tumour growth in mouse xenograft models.
- References
-
- CAS:342639-96-7
- PMID:21078672
- PMID:26100943
- PMID:27777286
- PMID:28859986
- PMID:29391353
- PMID:30995664
- PMID:31540279
- PMID:32334836
- PMID:33917524
- PMID:34107992
- PMID:34203709
- PMID:34299435
- PMID:34845571
- PMID:34922589
- PMID:35217815
- PMID:35268755
- PMID:35370703
- PMID:35434944
- PMID:36622366
- PMID:36700826
- PMID:37075668
- PMID:37165174
- PMID:38176599
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Phenotype
Phenotype resulting from KRIBB11
Phenotype where environments contain KRIBB11
Phenotype modified by environments containing KRIBB11
Human Disease Model