Search Ontology:
ChEBI
KRIBB11
- Term ID
- CHEBI:228800
- Synonyms
-
- N(2)-(1H-indazol-5-yl)-N(6)-methyl-3-nitropyridine-2,6-diamine
- N(2)-1H-indazol-5-yl-N(6)-methyl-3-nitro-2,6-pyridinediamine
- Definition
- A member of the class of indazoles that is 1H-indazole substituted by a [6-(methylamino)-3-nitropyridin-2-yl]amino group at position 5. It is an inhibitor of heat shock factor 1 (IC50 = 1.2μM) and suppresses tumour growth in mouse xenograft models.
- References
-
- cas:342639-96-7
- pubmed:21078672
- pubmed:26100943
- pubmed:27777286
- pubmed:28859986
- pubmed:29391353
- pubmed:30995664
- pubmed:31540279
- pubmed:32334836
- pubmed:33917524
- pubmed:34107992
- pubmed:34203709
- pubmed:34299435
- pubmed:34845571
- pubmed:34922589
- pubmed:35217815
- pubmed:35268755
- pubmed:35370703
- pubmed:35434944
- pubmed:36622366
- pubmed:36700826
- pubmed:37075668
- pubmed:37165174
- pubmed:38176599
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from KRIBB11
Phenotype where environments contain KRIBB11
Phenotype modified by environments containing KRIBB11
Phenotype affecting KRIBB11
Human Disease Model