Search Ontology:
ChEBI
LLY-507
- Term ID
- CHEBI:228258
- Synonyms
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- 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}-N-[3-(pyrrolidin-1-yl)propyl][biphenyl]-3-carboxamide
- LLY 507
- LLY507
- Definition
- A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}[biphenyl]-3-carboxylic acid with the amino group of 3-(pyrrolidin-1-yl)propan-1-amine. It is a potent and selective inhibitor of SMYD2 and inhibits the ability of SMYD2 to methylate p53. It serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes.
- References
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Show All 7 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from LLY-507
Phenotype where environments contain LLY-507
Phenotype modified by environments containing LLY-507
Human Disease / Model Data
Citations