Search Ontology:
ChEBI
KU-60019
- Term ID
- CHEBI:228206
- Synonyms
-
- 2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-N-{5-[6-(morpholin-4-yl)-4-oxo-4H-pyran-2-yl]-9H-thioxanthen-2-yl}acetamide
- KU 60019
- KU60019
- Definition
- A secondary carboxamide resulting from the formal condensation of the carboxy group of [(2R,6S)-2,6-dimethylmorpholin-4-yl]acetic acid with the amino group of 2-(7-amino-9H-thioxanthen-4-yl)-6-(morpholin-4-yl)-4H-pyran-4-one. It is an ATM kinase inhibitor (IC50 = 6.3 nM).
- References
-
- CAS:925701-46-8
- CAS:925701-49-1
- LINCS:LSM-1156
- PMID:19808981
- PMID:23620409
- PMID:24443327
- PMID:25091220
- PMID:25289090
- PMID:26620371
- PMID:28693235
- PMID:29522753
- PMID:31299316
- PMID:31597711
- PMID:31626963
- PMID:33971260
- PMID:34433825
- PMID:35477555
- PMID:35734412
- PMID:35783188
- PMID:35795059
- PMID:35835838
- PMID:36228747
- PMID:36314821
- PMID:36510329
- PMID:36650267
- PMID:36941082
- PMID:37620619
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Show first 5 Terms
Phenotype
Phenotype resulting from KU-60019
Phenotype where environments contain KU-60019
Phenotype modified by environments containing KU-60019
Human Disease / Model Data
Citations