Search Ontology:
ChEBI
KU-60019
- Term ID
- CHEBI:228206
- Synonyms
-
- 2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-N-{5-[6-(morpholin-4-yl)-4-oxo-4H-pyran-2-yl]-9H-thioxanthen-2-yl}acetamide
- KU 60019
- KU60019
- Definition
- A secondary carboxamide resulting from the formal condensation of the carboxy group of [(2R,6S)-2,6-dimethylmorpholin-4-yl]acetic acid with the amino group of 2-(7-amino-9H-thioxanthen-4-yl)-6-(morpholin-4-yl)-4H-pyran-4-one. It is an ATM kinase inhibitor (IC50 = 6.3 nM).
- References
-
- cas:925701-46-8
- cas:925701-49-1
- lincs.smallmolecule:LSM-1156
- pubmed:19808981
- pubmed:23620409
- pubmed:24443327
- pubmed:25091220
- pubmed:25289090
- pubmed:26620371
- pubmed:28693235
- pubmed:29522753
- pubmed:31299316
- pubmed:31597711
- pubmed:31626963
- pubmed:33971260
- pubmed:34433825
- pubmed:35477555
- pubmed:35734412
- pubmed:35783188
- pubmed:35795059
- pubmed:35835838
- pubmed:36228747
- pubmed:36314821
- pubmed:36510329
- pubmed:36650267
- pubmed:36941082
- pubmed:37620619
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from KU-60019
Phenotype where environments contain KU-60019
Phenotype modified by environments containing KU-60019
Phenotype affecting KU-60019
Human Disease Model