cefoxitin

Term ID

CHEBI:209807

Synonyms

• (6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7S)-4-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 3-[(carbamoyloxy)methyl]-7alpha-methoxy-7beta-[(thiophen-2-yl)acetamido]-3,4-didehydrocepham-4-carboxylic acid
• cefoxitin
• cefoxitina
• cefoxitine
• cefoxitinum
• ceftoxitin
• Cephoxitin
• CFX
• Rephoxitin

Definition

A semisynthetic cephamycin antibiotic which, in addition to the methoxy group at the 7α position, has 2-thienylacetamido and carbamoyloxymethyl side-groups. It is resistant to β-lactamase.

References

• beilstein:4216947
• cas:35607-66-0
• drugbank:DB01331
• drugcentral:550
• hmdb:HMDB0015426
• kegg.compound:C06887
• kegg.drug:D02345
• lincs.smallmolecule:LSM-5786
• patent:DE2129675
• patent:DE2203653
• patent:US4297488
• pdb-ccd:CFX
• pubmed:12569987
• pubmed:17043131
• pubmed:17178800
• pubmed:17220412
• pubmed:17353248
• pubmed:17387156
• pubmed:17923492
• pubmed:18056283
• pubmed:18070972
• pubmed:2083978
• pubmed:29017833
• pubmed:8360877
• reaxys:4216947
• wikipedia.en:Cefoxitin

Ontology

ChEBI  ( EBI )

Resources

CTD