Search Ontology:
ChEBI
poziotinib
- Term ID
- CHEBI:195559
- Synonyms
-
- 1-(4-{[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxy}piperidin-1-yl)prop-2-en-1-one
- 1-[4-[[4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one
- HM 781-36B
- Definition
- A member of the class of quinazolines that is quinazoline substituted by (3,4-dichloro-2-fluorophenyl)amino, [1-(prop-2-enoyl)piperidin-4-yl]oxy, and methoxy groups at positions 4, 6, and 7, respectively. It is a potent and irreversible tyrosine kinase inhibitor targeting EGFR and HER2 with exon 20 insertion mutations.
- References
-
- CAS:1092364-38-9
- Chemspider:30687714
- DrugBank:DB12114
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from poziotinib
Phenotype where environments contain poziotinib
Phenotype modified by environments containing poziotinib
Phenotype affecting poziotinib
Human Disease Model