Search Ontology:
ChEBI
NPD6433
- Term ID
- CHEBI:195528
- Synonyms
-
- methyl 3-[(E)-(8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl)diazenyl]-1H-indole-2-carboxylate
- Definition
- An indolyl carboxylate ester that is 1H-indole substituted by methoxycarbonyl and (E)-(8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl)diazenyl groups at positions 2 and 3, respectively. It targets the enoyl reductase domain of fungal fatty acid synthase, exhibits broad-spectrum antifungal activity, is bioactive against the filamentous mold, Aspergillus fumigatus and has minimal mammalian cytotoxicity.
- References
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
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Phenotype
Phenotype resulting from NPD6433
Phenotype where environments contain NPD6433
Phenotype modified by environments containing NPD6433
Human Disease Model