Search Ontology:
ChEBI
leucettine L41
- Term ID
- CHEBI:195521
- Synonyms
-
- (5Z)-2-anilino-5-(1,3-benzodioxol-5-ylmethylidene)-3,5-dihydro-4H-imidazol-4-one
- Definition
- A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a (2-anilino-5-oxo-1,5-dihydro-4H-imidazol-4-ylidene)methyl group at position 5. It is an inhibitor of DYRK1A, DYRK2, CLK1, and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 μM, respectively).
- References
-
- cas:1112978-84-3
- pubmed:21615147
- pubmed:22998443
- pubmed:23454515
- pubmed:24366666
- pubmed:25264830
- pubmed:26381812
- pubmed:30115750
- pubmed:30885273
- pubmed:31861110
- pubmed:34090874
- pubmed:35841249
- pubmed:37195917
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from leucettine L41
Phenotype where environments contain leucettine L41
Phenotype modified by environments containing leucettine L41
Phenotype affecting leucettine L41
Human Disease Model