NBI-31772

Term ID

CHEBI:195417

Synonyms

• 1-(3',4'-dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acid
• 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid
• 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acid
• 6,7-dihydroxy-1-(3,4-dihydroxybenzoyl)isoquinoline-3-carboxylic acid
• NBI 31772
• NBI31772

Definition

An isoquinoline substituted by 3,4-dihydroxybenzoyl, carboxy, hydroxy, and hydroxy groups at positions 1, 3, 6, and 7, respectively. It is a potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP).

References

• cas:374620-70-9
• chemspider:21379078
• pubmed:11445558
• pubmed:11689087
• pubmed:12749900
• pubmed:12749901
• pubmed:14526226
• pubmed:15380039
• pubmed:16091781
• pubmed:17342171
• pubmed:17482135
• pubmed:17823291
• pubmed:18938163
• pubmed:27689414
• pubmed:28611445
• pubmed:29209278
• pubmed:29292168
• pubmed:31170402
• pubmed:33442906

Ontology

ChEBI  ( EBI )