artemether

Term ID

CHEBI:195280

Synonyms

• (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane
• (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepine
• 10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
• artemetero
• artemether
• artemetherum
• artemisininelactol methyl ether
• beta-artemether
• beta-dihydroartemisinin methyl ether
• dihydroartemisinin methyl ether
• methyl-dihydroartemisinine

Definition

An artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria.

References

• Beilstein:6569878
• CAS:71963-77-4
• DrugBank:DB06697
• Drug_Central:245
• KEGG:D02483
• LINCS:LSM-5519
• PMID:11141088
• PMID:12781185
• PMID:16033274
• PMID:17242150
• PMID:17404003
• PMID:18243702
• PMID:3279208
• Wikipedia:Artemether

Ontology

ChEBI  ( EBI )

Resources

CTD