2-(3,4-dimethoxyphenyl)-9-[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]purine-6-carboxamide

Term ID

CHEBI:194300

Synonyms

2-(3,4-dimethoxyphenyl)-9-[4-(4-methylpiperazin-1-yl)-3-nitrophenyl]-9H-purine-6-carboxamide

Definition

A member of the clas of purines that is 9H-purine substituted by 3,4-dimethoxyphenyl, aminocarbonyl, and 4-(4-methylpiperazin-1-yl)-3-nitrophenyl groups at positions 2, 6 and 9, respectively. It is an inhibitor of EGFR and a potential anticancer agent.

References

PMID:33479688

Ontology

ChEBI ( EBI )

Relationships

is a type of: C-nitro compound dimethoxybenzene N-arylpiperazine N-methylpiperazine primary carboxamide ... Show All 6 Terms

C-nitro compound dimethoxybenzene N-arylpiperazine N-methylpiperazine primary carboxamide purines Show first 5 Terms
has_role: epidermal growth factor receptor antagonist

epidermal growth factor receptor antagonist Show first 5 Terms

Phenotype

Phenotype resulting from 2-(3,4-dimethoxyphenyl)-9-[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]purine-6-carboxamide

Phenotype where environments contain 2-(3,4-dimethoxyphenyl)-9-[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]purine-6-carboxamide

Phenotype modified by environments containing 2-(3,4-dimethoxyphenyl)-9-[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]purine-6-carboxamide

Human Disease / Model Data