yoda 1

Term ID

CHEBI:194079

Synonyms

2-((2,6-dichlorobenzyl)thio)-5-(pyrazin-2-yl)-1,3,4-thiadiazole
2-(5-{[(2,6-dichlorophenyl)methyl]sulfanyl}-1,3,4-thiadiazol-2-yl)pyrazine
2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]-pyrazine
2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine
2-{5-[(2,6-dichlorobenzyl)sulfanyl]-1,3,4-thiadiazol-2-yl}pyrazine
GlyT2-IN-1
yoda-1
yoda1

Definition

A member of the class of thiadiazoles that is 1,3,4-thiadiazole substituted by pyrazin-2-yl and (2,6-dichlorobenzyl)sulfanediyl groups at positions 2 and 5, respectively. It is a selective activator of mechanosensitive channel piezo1.

References

cas:448947-81-7
pubmed:29428723
pubmed:29498036
pubmed:29757938
pubmed:29795280
pubmed:31437459
pubmed:31582801
pubmed:31597314
pubmed:32523536
pubmed:33208899
pubmed:33549548
pubmed:33580124
pubmed:33610907
pubmed:34097801
pubmed:34360605
pubmed:35428847
pubmed:35552510
pubmed:35725398
pubmed:35858335
pubmed:35884459
pubmed:35942515
pubmed:35954193
pubmed:36120469
pubmed:36361659
pubmed:36447422
pubmed:36457052
pubmed:36457143
wikipedia.en:Yoda1

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from yoda 1

Phenotype where environments contain yoda 1

Phenotype modified by environments containing yoda 1

Phenotype affecting yoda 1

Human Disease Model