(-)-N(6)-(2-phenylisopropyl)adenosine

Term ID

CHEBI:192091

Synonyms

(-)-(phenylisopropyl)adenosine
(-)-N(6)-(2-phenylisopropyl)adenosine
(-)-N-(alpha-methylphenethyl)adenosine
(-)-PIA
(R)-(-)-N(6)-phenylisopropyladenosine
(R)-(phenylisopropyl)adenosine
(R)-N(6)-(1-methyl-2-phenylethyl)adenosine
(R)-N(6)-(2-phenylisopropyl)adenosine
(R)-N(6)-phenylisopropyladenosine
(R)-N-(phenylisopropyl)adenosine
(R)-PIA
L-2-N(6)-(phenylisopropyl)adenosine
L-phenylisopropyladenosine
L-PIA
N(6)-(L-2-phenylisopropyl)adenosine
N(6)-(R)-phenylisopropyladenosine
N(6)-[(R)-1-methyl-2-phenylethyl]adenosine
N(6)-D-phenylisopropyladenosine
N-[(2R)-1-phenylpropan-2-yl]adenosine
R(-)-N(6)-(2-phenylisopropyl)adenosine
R(-)-PIA
R-(-)-N(6)-2-phenylisopropyladenosine
R-(-)-PIA
R-phenylisopropyladenosine
R-PIA

Definition

A hydrocarbyladenosine in which adenosine is substituted at N-6 by a (2R)-1-phenylpropan-2-yl group. It is a potent adenosine A₁ receptor agonist that exhibits neuroprotective and antinociceptive properties.

References

cas:38594-96-6
chemspider:84148
patent:WO2021099832
pubmed:10487382
pubmed:10647703
pubmed:12354564
pubmed:12411402
pubmed:12742235
pubmed:14993103
pubmed:15673876
pubmed:1860043
pubmed:1873873
pubmed:18756057
pubmed:20850530
pubmed:20924638
pubmed:20957068
pubmed:21543780
pubmed:21852200
pubmed:21946103
pubmed:22266063
pubmed:2251328
pubmed:23994158
pubmed:2408594
pubmed:2702488
pubmed:27053204
pubmed:27068216
pubmed:3030132
pubmed:32046474
pubmed:33689481
pubmed:33919533
pubmed:4065271
pubmed:6302428
pubmed:6497845
pubmed:8214657
reaxys:4912716

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from (-)-N(6)-(2-phenylisopropyl)adenosine

Phenotype where environments contain (-)-N(6)-(2-phenylisopropyl)adenosine

Phenotype modified by environments containing (-)-N(6)-(2-phenylisopropyl)adenosine

Phenotype affecting (-)-N(6)-(2-phenylisopropyl)adenosine

Human Disease Model