arachidonyl-2'-chloroethylamide

Term ID

CHEBI:191854

Synonyms

• (5Z,8Z,11Z,14Z)-N-(2-chloroethyl)-5,8,11,14-eicosatetraenamide
• (5Z,8Z,11Z,14Z)-N-(2-chloroethyl)icosa-5,8,11,14-tetraenamide
• ACEA
• arachidonyl-2-chloroethylamide
• N-(2-chloroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide

Definition

A fatty amide obtained by the formal condensation of arachidonic acid with 2-chloroethanamine. It is a potent agonist of the CB1 receptor (Ki = 1.4 nM) and also has a low affinity for the CB2 receptor (Ki = 3100 nM).

References

• CAS:220556-69-4
• Chemspider:4470547
• HMDB:HMDB0247891
• PMID:10336536
• PMID:12095655
• PMID:15006899
• PMID:15277316
• PMID:15493300
• PMID:16649551
• PMID:16930590
• PMID:18362599
• PMID:19751793
• PMID:25881484
• PMID:25904357
• PMID:26820679
• PMID:27663280
• PMID:28441341
• PMID:28859122
• PMID:30552944
• PMID:30607903
• PMID:32413434
• PMID:33083022
• PMID:33220269
• PMID:34090883
• PMID:35189809
• Wikipedia:Arachidonyl-2'-chloroethylamide

Ontology

ChEBI  ( EBI )