Search Ontology:
ChEBI
PB28
- Term ID
- CHEBI:189648
- Synonyms
-
- 1-(3-(5-methoxytetralin-1-yl)propyl)-4-cyclohexylpiperazine
- 1-cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine
- 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl]piperazine
- 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine
- PB 28
- PB-28
- Definition
- A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (σ2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities.
- References
-
- cas:172906-90-0
- chemspider:8649746
- pubmed:15322732
- pubmed:16687172
- pubmed:16891467
- pubmed:18178434
- pubmed:19200007
- pubmed:19842660
- pubmed:20021355
- pubmed:20077462
- pubmed:21229979
- pubmed:21684636
- pubmed:21744858
- pubmed:22890883
- pubmed:23399765
- pubmed:24697311
- pubmed:25637276
- pubmed:28086830
- pubmed:28764962
- pubmed:29438891
- pubmed:31994091
- pubmed:33052254
- pubmed:33364961
- pubmed:34783163
- wikipedia.en:PB-28
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from PB28
Phenotype where environments contain PB28
Phenotype modified by environments containing PB28
Phenotype affecting PB28
Human Disease Model