Search Ontology:
ChEBI

PB28

Term ID
CHEBI:189648
Synonyms
  • 1-(3-(5-methoxytetralin-1-yl)propyl)-4-cyclohexylpiperazine
  • 1-cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine
  • 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl]piperazine
  • 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine
  • PB 28
  • PB-28
Definition
A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (sigma2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from PB28
Phenotype where environments contain PB28
Phenotype modified by environments containing PB28
Human Disease / Model Data
Citations
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