Search Ontology:
ChEBI
AR-42
- Term ID
- CHEBI:188197
- Synonyms
-
- (S)-HDAC 42
- (S)-HDAC-42
- AR 42
- Definition
- A secondary carboxamide resulting from the formal condensation of the carboxy group of (2S)-3-methyl-2-phenylbutanoic acid with the amino group of 4-amino-N-hydroxybenzamide. It is a pan-HDAC inhibitor that was in clinical development for the treatment of hematological malignancies and solid tumours.
- References
-
- CAS:935881-37-1
- Chemspider:5294039
- DrugBank:DB12707
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from AR-42
Phenotype where environments contain AR-42
Phenotype modified by environments containing AR-42
Phenotype affecting AR-42
Human Disease Model