LY-367,265

Term ID

CHEBI:183634

Synonyms

• 1-{2-[4-(6-fluoro-1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]ethyl}-5,6-dihydro-1H,4H-[1,2,5]thiadiazolo[4,3,2-ij]quinoline 2,2-dioxide
• 1-{2-[4-(6-fluoro-1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]ethyl}-5,6-dihydro-4H-2lambda(6)-[1,2,5]thiadiazolo[4,3,2-ij]quinoline-2,2(1H)-dione
• LY 367265
• LY-367265
• LY367265

Definition

A fluoroindole that is 1H-indole in which the hydrogens at positions 3 and 6 are replaced by 1-[2-(2,2-dioxo-5,6-dihydro-4H-2λ⁶-[1,2,5]thiadiazolo[4,3,2-ij]quinolin-1(2H)-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl and fluoro groups, respectively. It is an inhibitor of the 5-hydroxytryptamine transporter (Ki = 2.3 nM) and an antagonist of 5-hydroxytryptamine(2A) receptor (Ki = 0.81 nM).

References

• cas:210751-39-6
• chemspider:3797242
• pubmed:11050288
• pubmed:15602751
• pubmed:20149649
• pubmed:21616779
• pubmed:21823597
• pubmed:24134630
• wikipedia.en:LY-367,265

Ontology

ChEBI  ( EBI )