methoxsalen

Term ID

CHEBI:18358

Synonyms

• 6-hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone
• 8-methoxy-2',3',6,7-furocoumarin
• 8-methoxy-4',5':6,7-furocoumarin
• 8-methoxy-[furano-3'.2':6.7-coumarin]
• 8-Methoxyfuranocoumarin
• 8-Methoxypsoralen
• 8-MOP
• 8-MP
• 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one
• 9-methoxy-7H-furo[3,2-g]chromen-7-one
• Meladinine
• Meloxine
• METHOXSALEN
• O-methylxanthotoxol
• Oxsoralen
• Ultra Mop
• Uvadex
• Xanthotoxin

Definition

A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis.

References

• Beilstein:196453
• CAS:298-81-7
• DrugBank:DB00553
• Drug_Central:30
• HMDB:HMDB0014693
• KEGG:C01864
• KEGG:D00139
• KNApSAcK:C00000576
• LINCS:LSM-3410
• PDBeChem:8MO
• PMID:15009205
• PMID:28166217
• PMID:7945434
• Patent:US2889337
• Reaxys:196453
• Wikipedia:Methoxsalen

Ontology

ChEBI  ( EBI )

Resources

CTD