indirubin

Term ID

CHEBI:183083

Synonyms

• 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one
• 3-(3-oxo-1,3-dihydro-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one
• 3-(3-oxo-1H-indol-2-ylidene)-1H-indol-2-one
• [Delta(2,3')-biindoline]-2',3-dione
• C.I. 73200
• couroupitine B
• indigo red
• indigopurpurin

Definition

A member of the class of indolones that is 1,3-dihydro-2H-indol-2-one substituted by a 3-oxo-1,3-dihydro-2H-indol-2-ylidene group at position 3. It is the active component of Dang Gui Long Hui Wan, which has been used in traditional Chinese medicine to treat inflammatory diseases and chronic myeloid leukemia.

References

• CAS:479-41-4
• DrugBank:DB12379
• HMDB:HMDB0240743
• KNApSAcK:C00026982
• LINCS:LSM-42899
• PMID:21207415
• PMID:22363408
• PMID:31652913
• PMID:31796845
• PMID:32093032
• PMID:32795328
• PMID:32914538
• PMID:32927253
• PMID:32975633
• PMID:33283739
• PMID:33611057
• PMID:34135755
• PMID:34161865
• PMID:34280616
• PMID:34366843
• PMID:34396002
• Reaxys:88279
• Wikipedia:Indirubin

Ontology

ChEBI  ( EBI )

Resources

CTD