Search Ontology:
ChEBI

midafotel

Term ID
CHEBI:180900
Synonyms
  • (2R)-4-[(2E)-3-phosphono-2-propenyl]-2-piperazinecarboxylic acid
  • (2R)-4-[(2E)-3-phosphonoprop-2-en-1-yl]piperazine-2-carboxylic acid
  • (R)-4-[(E)-3-phosphonoprop-2-enyl]piperazine-2-carboxylic acid
  • (R)-CPP-ene
  • D(-)CPPene
  • D-4-[(2E)-3-phosphono-2-propenyl]-2-piperazinecarboxylic acid
  • D-CPP-ene
  • D-CPPene
  • midafotel
  • midafotelum
  • SDZ EAA 494
  • SDZ-EAA 494
  • SDZ-EAA-494
Definition
A member of the class of piperazines that is piperazine substituted by a carboxy group at position 2R and a (1E)-1-phosphonoprop-1-en-3-yl group at position 4. It is an antagonist of N-methyl-D-aspartate receptors (NMDARs) and was in clinical development by Novartis for the treatment of cognition disorders and brain injuries (now discontinued).
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from midafotel
Phenotype where environments contain midafotel
Phenotype modified by environments containing midafotel
Human Disease / Model Data