Search Ontology:
ChEBI
RK-24466
- Term ID
- CHEBI:180499
- Synonyms
-
- 4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[3,2-d]pyrimidin-7-yl-cyclopentane
- 7-cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- 7-cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine
- KIN 001-51
- KIN001-051
- RK 24466
- RK24466
- Definition
- A member of the class of pyrrolopyrimidines that is 7H-pyrrolo[2,3-d]pyrimidine substituted by amino, 4-phenoxyphenyl, and cyclopentyl groups at positions 4, 5 and 7, respectively. It is a potent inhibitor of Lck that inhibits Lck (64-509) and LckCD isoforms (IC50 of less than 1 and 2 nM, respectively).
- References
-
- CAS:213743-31-8
- Chemspider:5036104
- PMID:11012021
- PMID:23505068
- PMID:24134630
- PMID:28185804
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
Show first 5 Terms
Phenotype
Phenotype resulting from RK-24466
Phenotype where environments contain RK-24466
Phenotype modified by environments containing RK-24466
Human Disease / Model Data
Citations