Search Ontology:
ChEBI

oncrasin-1

Term ID
CHEBI:178196
Synonyms
  • 1-(4-chlorobenzyl)-1H-indole-3-carbaldehyde
  • 1-(p-chlorobenzyl)-1H-indole-3-carbaldehyde
  • 1-[(4-chlorophenyl)methyl]-1H-indole-3-carbaldehyde
  • ONC-1
  • oncrasin 1
Definition
A member of the class of indoles that is 1H-indole substituted by 4-chlorobenzyl and formyl groups at positions 1 and 3, respectively. It is an anti-cancer agent that is active against lung cancer cells with K-Ras mutations.
References
  • cas:75629-57-1
  • chemspider:761753
  • patent:US2009286847
  • pubmed:18794128
  • pubmed:19208825
  • pubmed:21443218
  • pubmed:22174819
  • pubmed:25874341
  • pubmed:32019870
  • pubmed:32727562
  • pubmed:33169204
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from oncrasin-1
Phenotype where environments contain oncrasin-1
Phenotype modified by environments containing oncrasin-1
Phenotype affecting oncrasin-1
Human Disease Model