Search Ontology:
ChEBI

L-817818

Term ID
CHEBI:177199
Synonyms
  • (2S)-2-aminopropyl (2R)-6-amino-2-{2-[2-(naphthalen-2-yl)-1H-benzo[g]indol-3-yl]acetamido}hexanoate
  • (2S)-2-aminopropyl N(2)-{[2-(naphthalen-2-yl)-1H-benzo[g]indol-3-yl]acetyl}-D-lysinate
  • L 817818
  • L-817,818
  • L817818
Definition
A benzoindole that is 1H-benzo[g]indole substituted by naphthalen-2-yl and 2-({(2R)-6-amino-1-[(2S)-2-aminopropoxy]-1-oxohexan-2-yl}amino)-2-oxoethyl groups at positions 2 and 3, respectively. It is a selective nonpeptidic agonist of the somatostatin subtype-5 (SST5) receptor with Ki of 0.4 nM.
References
  • cas:217480-27-8
  • chemspider:8112641
  • pubmed:10433861
  • pubmed:10614629
  • pubmed:11087999
  • pubmed:11514055
  • pubmed:11532069
  • pubmed:12746229
  • pubmed:16081634
  • pubmed:18210999
  • pubmed:19067538
  • pubmed:19576912
  • pubmed:21539874
  • pubmed:27686614
  • pubmed:29719449
  • pubmed:30020824
  • pubmed:31220522
  • pubmed:31895741
  • pubmed:33465395
  • pubmed:9784130
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from L-817818
Phenotype where environments contain L-817818
Phenotype modified by environments containing L-817818
Phenotype affecting L-817818
Human Disease Model