Search Ontology:
ChEBI
ML162
- Term ID
- CHEBI:176499
- Synonyms
-
- 2-chloro-N-(3-chloro-4-methoxyphenyl)-N-{2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl}acetamide
- DPI7
- ML 162
- ML-162
- Molecular Libraries 162
- Definition
- A monochlorobenzene that is benzene substituted by (chloroacetyl){2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl}amino, chloro and methoxy groups at positions 1, 3 and 4, respectively. It is a covalent inhibitor of glutathione peroxidase 4 (GPX4) that induces ferroptosis in cells.
- References
-
- CAS:1035072-16-2
- Chemspider:2921671
- LINCS:LSM-1493
- PMID:22297109
- PMID:22832321
- PMID:27048822
- PMID:30339884
- PMID:33559612
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
Phenotype
Phenotype resulting from ML162
Phenotype where environments contain ML162
Phenotype modified by environments containing ML162
Human Disease / Model Data
Citations