Search Ontology:
ChEBI

GSK2879552

Term ID
CHEBI:176334
Synonyms
  • 4-{[4-({[(1R,2S)-2-phenylcyclopropyl]amino}methyl)piperidin-1-yl]methyl}benzoic acid
  • GSK 2879552
  • GSK-2879552
Definition
A member of the class of piperidines that is piperidine substituted by (4-carboxyphenyl)methyl and {[(1R,2S)-2-phenylcyclopropyl]amino}methyl groups at positions 1 and 4, respectively. It is a potent and irreversible inhibitor of lysine specific demethylase 1 (LSD1, also known as KDM1A). It was under clinical investigation for the treatment of acute myeloid leukaemia and small cell lung carcinoma.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from GSK2879552
Phenotype where environments contain GSK2879552
Phenotype modified by environments containing GSK2879552
Human Disease / Model Data
Citations
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