liproxstatin-1

Term ID

CHEBI:173097

Synonyms

Lip-1
liproxstatin 1
liproxstatin1
N-(3-chlorobenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine
N-[(3-chlorophenyl)methyl]-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine

Definition

An azaspiro compound that is 1'H-spiro[piperidine-4,2'-quinoxaline] in which the hydrogen at position 3' is replaced by a (3-chlorobenzyl)amino group. It is a potent inhibitor of ferroptosis.

References

cas:950455-15-9
chemspider:20387119
pubmed:28386601
pubmed:28489094
pubmed:28975372
pubmed:31597407
pubmed:31623831
pubmed:31655003
pubmed:31682397
pubmed:32540488
pubmed:32985488
pubmed:33314758
pubmed:33343803
pubmed:33378529
pubmed:33421025
pubmed:33453994
pubmed:33497529
pubmed:33681224
pubmed:33735625
pubmed:33827043
pubmed:33889074
pubmed:33974796

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from liproxstatin-1

Phenotype where environments contain liproxstatin-1

Phenotype modified by environments containing liproxstatin-1

Phenotype affecting liproxstatin-1

Human Disease Model