Search Ontology:
ChEBI

garomefrine hydrochloride

Term ID
CHEBI:167680
Synonyms
  • (-)-garomefrine hydrochloride
  • (2R)-2-{2-fluoro-5-[(methylsulfonyl)amino]phenyl}-2-hydroxyethanaminium chloride
  • (R)-(-)-3'-(2-amino-1-hydroxyethyl)-4'-fluoromethanesulfonanilide hydrochloride
  • ABT-232
  • garomefrin hydrochloride
  • garomefrine monohydrochloride
  • N-{3-[(1R)-2-amino-1-hydroxyethyl]-4-fluorophenyl}methanesulfonamide hydrochloride
  • NS 49
  • NS-49
  • PNO-49B
  • PNO49B
Definition
A hydrochloride obtained by reaction of garomefrine with one equivalent of hydrochloric acid. It is a α1A adrenoreceptor agonist which was being developed for the treatment of urinary incontinence (now discontinued).
References
  • cas:137431-04-0
  • chemspider:8014482
  • kegg.drug:D09784
  • pubmed:10367106
  • pubmed:10417870
  • pubmed:10425363
  • pubmed:10440796
  • pubmed:10442210
  • pubmed:10468772
  • pubmed:10486440
  • pubmed:10633163
  • pubmed:11367870
  • pubmed:11413740
  • pubmed:11413741
  • pubmed:7715737
  • pubmed:8719417
  • pubmed:9007522
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from garomefrine hydrochloride
Phenotype where environments contain garomefrine hydrochloride
Phenotype modified by environments containing garomefrine hydrochloride
Phenotype affecting garomefrine hydrochloride
Human Disease Model