MP-A08

Term ID

CHEBI:167665

Synonyms

• 4-methyl-N-[2-[[2-[(4-methylphenyl)sulfonylamino]phenyl]iminomethyl]phenyl]benzenesulfonamide
• 4-methyl-N-{2-[(2-{[(4-methylphenyl)sulfonyl]amino}benzylidene)amino]phenyl}benzenesulfonamide
• MP A08
• MPA08

Definition

A sulfonamide that consists of two moieties of 4-methyl-N-phenylbenzenesulfonamide connected to each other at position 2 by an aldimine linker. It is a ATP-competitive inhibitor of sphingosine kinase that targets both SK1 and SK2 (Ki values of 27 μM and 6.9 μM, respectively) and exhibits anti-cancer properties.

References

• cas:219832-49-2
• chemspider:24832025
• pubmed:25788259
• pubmed:26822263

Ontology

ChEBI  ( EBI )