Search Ontology:
ChEBI
BAYu9773
- Term ID
- CHEBI:167654
- Synonyms
-
- 4-{[(4S,5R,6E,8E,10Z,13Z)-1-carboxy-4-hydroxynonadeca-6,8,10,13-tetraen-5-yl]sulfanyl}benzoic acid
- 6(R)-(4-carboxyphenylthio)-5(S)-hydroxy-7(E),9(E),11(E),14(Z)-eicosatetraenoic acid
- BAY u9773
- BAY-u 9773
- BAY-u9773
- Definition
- A dicarboxylic acid that is that is (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid substituted by a hydroxy group at position 4S and a (4-carboxyphenyl)sulfanediyl group at 5R. It is a dual cysteinyl leukotriene receptor antagonist that acts at the CysLT1 and CysLT2 receptors (IC50 = 0.44 and 0.30 μM, respectively).
- References
-
- cas:154978-38-8
- chemspider:4470554
- pubmed:12466244
- pubmed:12598425
- pubmed:1659283
- pubmed:18315950
- pubmed:18503712
- pubmed:19118273
- pubmed:19563734
- pubmed:19941848
- pubmed:20014485
- pubmed:20423349
- pubmed:21396378
- pubmed:21646802
- pubmed:21903747
- pubmed:23801612
- pubmed:25408836
- pubmed:25707327
- pubmed:27198524
- pubmed:7698171
- pubmed:8982726
- pubmed:9597121
- pubmed:9797038
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from BAYu9773
Phenotype where environments contain BAYu9773
Phenotype modified by environments containing BAYu9773
Phenotype affecting BAYu9773
Human Disease Model