AZT-1152

Term ID

CHEBI:167636

Synonyms

2-[ethyl(3-{[4-({5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl}amino)quinazolin-7-yl]oxy}propyl)amino]ethyl dihydrogen phosphate
AZD1152-HQPA dihydrogen phosphate
AZD2811
barasertib
barasertibum
INH-34

Definition

A dihydrogen phosphate prodrug of a pyrazoloquinazoline aurora kinase inhibitor AZD1152-hydroxyquinazoline pyrazol anilide(HQPA) and is converted rapidly to the active AZD1152-HQPA in plasma.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: anilide monoalkyl phosphate monofluorobenzenes pyrazoles quinazolines ... Show All 8 Terms

anilide monoalkyl phosphate monofluorobenzenes pyrazoles quinazolines secondary amino compound secondary carboxamide tertiary amino compound Show first 5 Terms
has_functional_parent: AZD-1152

AZD-1152 Show first 5 Terms
has_role: antineoplastic agent Aurora kinase inhibitor prodrug

antineoplastic agent Aurora kinase inhibitor prodrug Show first 5 Terms

Phenotype

Phenotype resulting from AZT-1152

Phenotype where environments contain AZT-1152

Phenotype modified by environments containing AZT-1152

Human Disease / Model Data

Citations