Search Ontology:
ChEBI

phevalin

Term ID
CHEBI:167320
Synonyms
  • 3-(1-methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone
  • 6-benzyl-3-(propan-2-yl)-1,2-dihydropyrazin-2-one
  • 6-benzyl-3-(propan-2-yl)pyrazin-2(1H)-one
  • 6-benzyl-3-isopropyl-1H-pyrazin-2-one
  • 6-benzyl-3-propan-2-yl-1H-pyrazin-2-one
  • aureusimine B
Definition
A member of the class of pyrazinones that is pyrazin-2(1H)-one substituted by an isopropyl and benzyl groups at position 3 and 6, respectively. It is a natural product found in Staphylococcus aureus that inhibits calpain in a casein hydrolysis assay (IC50 = 1.3 muM), contributes to S. aureus infection in mice, and alters human keratinocyte gene expression.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from phevalin
Phenotype where environments contain phevalin
Phenotype modified by environments containing phevalin
Human Disease / Model Data
Citations
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