fumisoquin A

Term ID

CHEBI:167211

Synonyms

(1S,3S,11R,11aR)-3-amino-1,7,8,11-tetrahydroxy-1,2,3,6,11,11a-hexahydro-4H-pyrido[1,2-b]isoquinolin-4-one
(1S,3S,11R,11aR)-3-amino-1,7,8,11-tetrahydroxy-1H,2H,3H,4H,6H,11H,11aH-pyrido[1,2-b]isoquinolin-4-one

Definition

A pyridoisoquinoline that is (11aR)-1,3,4,6,11,11a-hexahydro-2H-pyrido[1,2-b]isoquinoline substituted by hydoxy groups at positions 1S,7,8 and 11R, by an amino group at position 3S and an oxo group at position 4. It is produced by a biosynthetic gene cluster called fsq in the human pathogen Aspergillus fumigatus.

References

KNApSAcK:C00051874
PMID:27065235

Ontology

ChEBI ( EBI )

Relationships

is a type of: isoquinoline alkaloid phenols primary amino compound pyridoisoquinoline tetrol

isoquinoline alkaloid phenols primary amino compound pyridoisoquinoline tetrol Show first 5 Terms
has_role: Aspergillus metabolite

Aspergillus metabolite Show first 5 Terms
inverse is_conjugate_acid_of: fumisoquin A(1+)

fumisoquin A(1+) Show first 5 Terms
is_conjugate_base_of: fumisoquin A(1+)

fumisoquin A(1+) Show first 5 Terms

Phenotype

Phenotype resulting from fumisoquin A

Phenotype where environments contain fumisoquin A

Phenotype modified by environments containing fumisoquin A

Human Disease Model